WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Review Journal for Medical Science and Pharma Professionals

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

World Journal of Advance Healthcare Research (WJAHR) has indexed with various reputed international bodies like : Google Scholar , Index Copernicus , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , Cosmos Impact Factor , Scientific Indexing Services (SIS) , UDLedge Science Citation Index , International Impact Factor Services , International Society for Research Activity (ISRA) Journal Impact Factor (JIF) , IFSIJ Measure of Journal Quality , Scientific Journal Impact Factor (SJIF) , International Scientific Indexing, UAE (ISI) (Under Process) , International Impact Factor Services (IIFS) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Academia , Scope Database , 

ISSN 2457-0400

Impact Factor  :  6.711

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  • 6th International Conference on Human and Soci

    Venue:FCT Education Resource Center, Abuja- Nigeria                                        September 22-24, 2019

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    6th INTERNATIONAL CONFERENCE ON EDUCATIONAL TECHNOLOGY AND CURRICULUM STUDIES(ICETC2019) 

     

    Venue: FCT Education Resource Center, Abuja-Nigeria

    September 22-24, 2019

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  • New Issue Published

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Best Paper Awards

World Journal of Advance Healthcare Research (WJAHR)Honored the authors with best paper award, monthly based on the innovation of research work. Best paper will be selected by our expert panel.

Best Article of current issue

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Indexing

Abstract

PROGNOSTIC SIGNIFICANCE OF BCL-2 AND BCL-6 IMMUNOSTAINING IN B-CELL NON-HODGKIN’S LYMPHOMA

Reem Kafa, MD*, Firas Hussein, MD and Ali Daoud, MD

ABSTRACT

Purpose: The aim of this study was to identify a possible effect of Bcl-2 and Bcl-6 proteins on the clinical behavior and outcome in different subtypes of B-cell non-Hodgkin lymphoma (B-NHL). Methods: We retrospectively studied Bcl-2 and Bcl-6 expression by immunohistochemistry (IHC) in 145 patients with diffuse large B-cell lymphoma (DLBCL), 86 patients with follicular lymphoma (FL), and 53 patients with mantle cell lymphoma (MCL), and analyzed their prognostic relevance and effect on treatment response in these cohorts. Results: Positive Bcl-2 expression related strongly to lower rates of complete response (CR) after first-line treatment with Rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) in both DLBCL (p=0.001) and MCL (p=0.01). Bcl-2 was recognized as an independent predictor of poor overall survival (OS) (HR=2.9, p

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