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Abstract
A PROSPECTIVE STUDY OF ADVERSE DRUG REACTIONS AND DRUG UTILIZATION PATTERN IN DERMATOLOGY DEPARTMENT
*Dr. J. Femi Retna and Dr. Amudavalli K.
ABSTRACT
Introduction: Dermatological diseases are long-lasting in nature and they need lifelong treatment mostly. Prescription pattern echoes dermatologists? attitude towards the disease and part of drugs in its treatment. Hence the study of drug utilization pattern and related adverse effect profile is important to make medical management balanced. Objective: To evaluate drug prescribing pattern and adverse drug reaction profile in Dermatology department of tertiary care hospital. Results: In our study 350 patient?s treatment were analyzed which include various drugs which account for around 1408. Majority of drugs prescribed were antihistamines (25.23%), antibacterial (18%), antifungal (12%), and corticosteroids (9%). Forty patients were reported with ADR. Most of ADRs are reported with Antimicrobials & common ADR was Maculopapular rash, on severity assessment by modified Hartwig and Siegel?s scale, out of 40 ADRs, 22 (55%) were mild, 14 (35%) were moderate and 4 (10%) were severe in nature. Based on Naranjo scale analysis 32 were possible 7 was probable and one was definite. Conclusion: The present study showed antihistaminic were commonly prescribed class & antibiotics were responsible from majority of ADR. Maculopapular rash was most common ADR.
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