WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

Dr. Nirranjana Sakthivelu and Dr. Divya Singh*

ABSTRACT

Background and Objectives: Acute Kidney Injury is synonymous with morbidity and mortality in critically ill children. Lack of standardization of existing definitions has led to the masking of true incidence of AKI. This study was done to compare the incidence of AKI in PICU and non ICU patients by pRIFLE, AKIN and KDIGO criteria. Material and Methods: A prospective observational study of 280 children, aged between 3 months and 18 years, admitted in ICU and general ward of Department of Pediatrics, Rajendra Institute of Medical Sciences, Jharkhand from January to August 2019 was undertaken. Incidence of AKI and staging were defined by pRIFLE, AKIN, and KDIGO definitions. Outcome and duration of stay at each AKI stage between the three definitions were compared by Fisher Exact tests. Results: AKI incidences according to pRIFLE, AKIN, and KDIGO were 37.8%, 27.8%, and 30% respectively. Mortality was alike across all definitions (pRIFLE, 2.3%; AKIN, 2.7%; KDIGO, 2.5%). Significantly longer hospital stay was noted, mean duration of ICU and non-ICU stay being 9 and 15 days respectively. Inter-stage incidence was similar between AKIN and KDIGO criteria. Conclusion: Since the three definitions led to differences in AKI incidence and staging, these results underscore the need to adopt an universal AKI definition.

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