WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Review Journal for Medical Science and Pharma Professionals

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

World Journal of Advance Healthcare Research (WJAHR) has indexed with various reputed international bodies like : Google Scholar , Index Copernicus , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , Cosmos Impact Factor , Scientific Indexing Services (SIS) , UDLedge Science Citation Index , International Impact Factor Services , International Society for Research Activity (ISRA) Journal Impact Factor (JIF) , IFSIJ Measure of Journal Quality , Scientific Journal Impact Factor (SJIF) , International Scientific Indexing, UAE (ISI) (Under Process) , International Impact Factor Services (IIFS) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Academia , Scope Database , 

ISSN 2457-0400

Impact Factor  :  6.711

News & Updation

  • Article Invited for Publication

    Dear Researcher, Article Invited for Publication  in WJAHR coming Issue.

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • 6th International Conference on Human and Soci

    Venue:FCT Education Resource Center, Abuja- Nigeria                                        September 22-24, 2019

  • .

    6th INTERNATIONAL CONFERENCE ON EDUCATIONAL TECHNOLOGY AND CURRICULUM STUDIES(ICETC2019) 

     

    Venue: FCT Education Resource Center, Abuja-Nigeria

    September 22-24, 2019

  • WJAHR: New Impact Factor

    WJAHR Impact Factor has been Increased to 6.711 for Year 2024.

  • New Issue Published

    Its Our pleasure to inform you that, WJAHR March 2023 Issue has been Published, Kindly check it on https://www.wjahr.com/home/current_issues

  • WJAHR: MARCH ISSUE PUBLISHED

    March 2024 Issue has been successfully launched on 1 March 2024.

Best Paper Awards

World Journal of Advance Healthcare Research (WJAHR)Honored the authors with best paper award, monthly based on the innovation of research work. Best paper will be selected by our expert panel.

Best Article of current issue

Download Article : Click here

Indexing

Abstract

EVALUATION OF NON-INVASIVE MARKERS OF FIBROSIS AND THEIR CORRELATION WITH THE VIRAL LOAD IN SUBJECTS WITH HEPATITIS B VIRUS IN NNEWI

Obiomah Chinwe Favour*, Amilo Grace I., Obeagu Emmanuel Ifeanyi and Vincent C. C. N.

ABSTRACT

Hepatitis B is an infectious disease of great public health importance. Nigeria is one of the countries with the highest incidence of Hepatitis B Virus (HBV) infection worldwide. However, the accessibility and affordability of HBV DNA quantification (viral load) assay which is the key laboratory test for therapy initiation, and monitoring is a challenge to HBV management. This study was designed to evaluate the non-invasive markers of fibrosis and their correlation with the viral load in subjects with hepatis B virus in Nnewi. Cross sectional study design was used with a total of 264 subjects comprising of 88 HBsAg seropositive treatment naïve subjects, 88 HBsAg seropositive subjects on antiviral therapy as case subjects and 88 age-matched apparently healthy HBsAg seronegative individuals were recruited as control subjects. Hepatitis B virus DNA assay was performed using real time PCR technique, Hepatitis C Virus assay, Human Immunodeficiency Virus testing, Gamma glutamyl transferase, Aspartate transaminase, Alanine transaminase tests were determined using spectrophotometric methods. Non-invasive markers of fibrosis - RDW-Platelet Ratio (RPR), Neutrophil to Lymphocyte ratio, Platelet to Lymphocyte ratio, GGT to Platelet ratio, AST-Platelet Ratio index and AST-ALT Ratio were calculated. The noninvasive markers of fibrosis –GGT to Platelet ratio, AST to platelet ratio and AST to ALT ratio were significantly higher in test subjects (0.06±0.11; 0.44±0.87; 1.49±0.86) compared with control subjects (0.02±0.01;0.11± 0.69;0.89±0.59 respectively, p

[Full Text Article] [Download Certificate]