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World Journal of Advance Healthcare Research (WJAHR)Honored the authors with best paper award, monthly based on the innovation of research work. Best paper will be selected by our expert panel.
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Abstract
COMPARATIVE ANALYSIS OF THE IMPACT OF HUMAN IMMUNE-DEFICIENCY VIRUS ON FERTILITY VARIABLES OF COMMERCIAL MOTOCYCLISTS AND NON-CYCLISTS IN NNEWI, SOUTH-EAST NIGERIA
Ochiabuto O. M. T. B.* and Chukwura. E. I.
ABSTRACT
Background: Human immunodeficiency virus infection (HIV), a global epidemic especially in high-risk occupational groups, impacts negatively on fertility parameters and male- fertility. Methodolgy: A case-control study of thecomparative analysis on the impact of Human Immune-deficiency Virus on fertility variables of commercial motorcyclists and non-cyclists in Nnewi, South-East Nigeriawas conducted. A total of 152 males consisting of 49 commercialmotorcyclists and 103 non-cyclists of age-ranges of 19-79 years old was used. Pre-tested questionnaires and tools were used for data collection for variables; hormones were assessed by immunoassay technique, HIV virus was screened immune-chromatographically using parallel testing, positive samples confirmed with Western-blot technique, semen biomarkers (FSH,LH, prolactin, progesterone, testosterone) by Enzyme Linked Imunosorbent Assay (ELISA), semen qualities with new WHO methods, modified to suit sperm; fertility index and observed fertility index was mathematically-derived. Biologically important semen quality parameters were calculatedwith standard WHO mathematical-deduction method. Results: Results revealed a total of 4(2.6%) were HIV-1 infected; 3(6.1%) from tests and 1(1.0%) from controls. Positive HIV status impacted negatively significantly on observed fertility status (U2 = 136.500; P = 0.049) in all males andsome semen quality variables; (teratozoospermia
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