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Abstract
MICROPAPULAR CUTANEOUS SARCOIDOSIS: CLINICODERMOSCOPIC AND HISTOPATHOLOGICAL CORRELATION
Mustafa Alperen Aydeniz*
ABSTRACT
Sarcoidosis is a multisystem inflammatory disease characterized by noncaseating granulomas, with cutaneous involvement presenting in various morphological patterns. Micropapular cutaneous sarcoidosis is a rare clinical variant that may pose a diagnostic challenge. We report a 64-year-old woman presenting with numerous yellowish-pink millimetric papules on the posterior trunk. Dermoscopy revealed multiple yellow-orange structureless areas on a pink background, while histopathological examination demonstrated non-necrotizing “naked” granulomas with multinucleated giant cells. Systemic evaluation revealed lymphopenia, elevated serum angiotensin-converting enzyme levels, hypercalciuria, and thoracic imaging abnormalities consistent with systemic involvement. Treatment with oral methylprednisolone and methotrexate resulted in complete clinical resolution of the cutaneous lesions within three months. This case emphasizes the value of clinicodermoscopic and histopathological correlation in recognizing this rare presentation and prompting evaluation for systemic disease.
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