WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

*Abdulhadi Mohammed Tarkh, Amer Ahmed Abdullah Al-Qaftan, Duraid Khalil Ibrahim

ABSTRACT

Background: Hypertension (HT) is a critical risk factor for the development of cardiovascular disease and a major public health concern. There are still a number of unclear issues about antihypertensive medication and LVH regression; one of the most important clinical questions is whether LVH is reversible or not. Objectives: To assess the factors associated with left ventricular hypertrophy among patients with optimum controlled hypertension. Methods: This is a cross-sectional study. Included adult patients aged more than 18 years old who had hypertension based on a history of prior diagnosis and therapy, blood pressure ≥ 140/90 mmHg on two to three office visits two weeks apart, home blood pressure readings >130/80 mmHg, or a single blood pressure reading of ≥180/110 mmHg. The study patients were assessed at the medical consultation clinic of Al-Shirqat General Hospital from August 2022 to October 2025. The questionnaire consisted from four sections. Section one for sociodemographic and anthropometric measurements, section two for baseline and follow up systolic, diastolic and heart rate measurements, section three for different clinical and biochemical variables and section four for Echocardiographic findings of the patients. Results: The study included 400 patients; 50 (12.5%) patients had left ventricular regression and 350 (87.5%) patients with no left ventricular regression. The mean age ± standard deviation of the study participants was 59.25 ± 10.72 years. Statistically significant difference between the two groups regarding their gender, smoking state, presence of obesity, mean of ages and mean of BMI (P value <0.05). In addition to that, statistically significant difference between the two groups with regard to their baseline and follow up means of systolic, diastolic blood pressure (P value <0.05) for all of them. Moreover, statistically significant difference between the two groups with regard to the presence of diabetes (P value = 0.019), and mean of estimated glomerular filtration rate (P value = 0.046). Conclusion: Certain factors significantly associated with decrease the possibility of LVH regression. These factors are female gender, elderly, smoking, obesity, higher systolic and diastolic blood pressure with prolonged duration, presence of diabetes and lower estimated glomerular filtration rate. Clinician should treat hypertensive patients as soon as possible with special attention to the presence of these factors.