WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

Dr. Arqam Ghazi Azeez*, Dr. Heba Hassan Basheer, Dr. Saif Abdulelah Mustafa Al Najar

ABSTRACT

Background: Type 2 diabetes mellitus (T2DM) accounts for 90% of diabetes globally, characterized by elevated blood sugar due to genetic and environmental factors. It presents major health risks via organ complications. HbA1C serves as a crucial biomarker for long-term glucose management. Additionally, C-reactive protein (CRP) levels, linked to systemic inflammation, are affected by lifestyle choices and medications. Aim: To evaluate the correlation of serum CRP with glycated hemoglobin among Iraqi diabetic patients. Patients and Methods: A cross-sectional study was conducted at Al-Salam Teaching Hospital in Nineveh Governorate, Iraq, focusing on patients with type 2 diabetes mellitus diagnosed according to WHO criteria, from January to June 2025. Exclusions included individuals with established cardiovascular disease, chronic kidney disease, infections, hemolytic anemia, and those on statins or NSAIDs. Informed consent was obtained, and blood samples were collected to measure HbA1c and high-sensitivity CRP (hsCRP) levels, with HbA1c. Results: In this analysis of 60 patients with DM, data showed a mean HbA1c of 9.57± 1.911 and mean hsCRP of 6.42±3.201. Patients were categorized into three groups based on HbA1c levels, revealing a progressive increase in mean CRP levels corresponding to higher HbA1c levels. A Pearson correlation coefficient indicated a positive linear relationship between CRP and HbA1c, with a statistically significant p-value of 0.020. Conclusion: A significant correlation is observed between C-reactive protein levels and HbA1c levels in diabetic patients, with higher HbA1c values indicating poorer long-term glycemic control associated with elevated CRP levels.