WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Review Journal for Medical Science and Pharma Professionals

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

World Journal of Advance Healthcare Research (WJAHR) has indexed with various reputed international bodies like : Google Scholar , Index Copernicus , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , Cosmos Impact Factor , Scientific Indexing Services (SIS) , UDLedge Science Citation Index , International Impact Factor Services , International Society for Research Activity (ISRA) Journal Impact Factor (JIF) , Scientific Journal Impact Factor (SJIF) , IFSIJ Measure of Journal Quality , International Scientific Indexing, UAE (ISI) (Under Process) , International Impact Factor Services (IIFS) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Academia , Scope Database , Research Publication Rating and Indexing , Doi-Digital Online Identifier , ISSN National Centre , Zenodo Indexing , International CODEN Service, USA , 

ISSN 2457-0400

Impact Factor  :  6.711

WJAHR Citation

  All Since 2020
 Citation  105  60
 h-index  4  4
 i10-index  3  2

News & Updation

  • Article Invited for Publication

    Dear Researcher, Article Invited for Publication  in WJAHR coming Issue.

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • 6th International Conference on Human and Soci

    Venue:FCT Education Resource Center, Abuja- Nigeria                                        September 22-24, 2019

  • .

    6th INTERNATIONAL CONFERENCE ON EDUCATIONAL TECHNOLOGY AND CURRICULUM STUDIES(ICETC2019) 

     

    Venue: FCT Education Resource Center, Abuja-Nigeria

    September 22-24, 2019

  • WJAHR: New Impact Factor

    WJAHR Impact Factor has been Increased to 6.711 for Year 2024.

  • WJAHR: OCTOBER ISSUE PUBLISHED

    OCTOBER 2025 Issue has been successfully launched on OCTOBER 2025.

  • New Issue Published

    Its Our pleasure to inform you that, WJAHR October 2025 Issue has been Published, Kindly check it on https://www.wjahr.com/home/current_issues

Best Article Awards

World Journal of Advance Healthcare Research (WJAHR) is giving Best Article Award in every Issue for Best Article and Issue Certificate of Appreciation to the Authors to promote research activity of scholar.

Best Article of current issue

Download Article : Click here

Indexing

Abstract

THE EFFECT OF HESPERIDEN & DIOSMIN MIXTURE ON GASTRIC ULCERS INDUCED BY INDOMETHACIN IN MICE

Marah Salamy*, Zeina Hamama and Rana Issa

ABSTRACT

Peptic ulcer is a lesion on the stomach lining known as a gastric ulcer or on the duodenum lining referred to as duodenal ulcers. This leads to a disruption of mucosal integrity. Non-Steroidal AntiInflammatory Drugs (NSAIDs) are primarily responsible for most cases of the disease. Flavonoids provide cytoprotective and restorative effects by enhancing protective factors such as mucus and prostaglandins, also by shielding against potentially harmful elements through their antioxidative, anti-inflammatory, and antibacterial activities. Therefore, this study aims to investigate the effect of Hesperidin and Diosmin Mixture (Hes&Dio) on gastric ulcers induced by Indomethacin in mice. Animals were divided into 4 groups (n= 6 in each): group 1 (Control, CMC), group 2 (Indomethacin), group 3 (Famotidine 8.3 mg/kg), group 4 (Hesperidin and Diosmin 615 mg/kg). Drugs were given orally for 15 days, and then gastric ulcers were induced by a single oral dose of Indomethacin (275 mg/kg) in the last day of the experiment. Histological findings revealed that the group of animals that received Indomethacin experienced ulceration of the entire mucosa, while pre-treatment with Hesperidin and Diosmin reduced ulceration and the depth of lesions in comparison to the Indomethacin group. There was no statistically significant difference observed between the Hes&Dio mixture group and the Famotidine group Our study was the only and the first study that evaluated the effectiveness of mixture of two components (Hesperidin and Diosmin) in Indomethacin induced gastric ulcers, in light of many researches that studied the effect of only one component of the mixture.

[Full Text Article] [Download Certificate]