WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

Kenzie Ongko Wijaya*, Nunki Puspita Utomo, Arya Taksya Bagaskara, Muhammad Andika Wibisono, Endro Basuki Sadjiman

ABSTRACT

Introduction: Motor Evoked Potential (MEP) monitoring is essential in intraoperative neuromonitoring (IONM) for assessing motor tract integrity and predicting postoperative neurological deficits (PONDs) in spinal surgeries. A decline in MEP signals during surgery indicates potential neurological injury. This review assesses the impact of MEP amplitude decline on postoperative outcomes. Objectives: To evaluate the effectiveness of intraoperative MEP monitoring in predicting motor outcomes in spinal surgeries. Materials and Methods: A systematic review of PubMed, ScienceDirect, and Cochrane Library was conducted, adhering to PRISMA guidelines. The MINORS tool assessed study quality. The correlation between MEP amplitude changes and outcomes was synthesized qualitatively. Results: Of 15 identified studies, 7 cohort studies were analyzed. Significant MEP amplitude declines (≥80%) consistently correlated with higher postoperative motor deficits, while improvements indicated better recovery. Conclusions: MEP monitoring reliably predicts motor outcomes in spinal surgeries, allowing for intraoperative adjustments to prevent neurological complications. Further research is needed to optimize monitoring protocols and establish long-term outcome thresholds.