WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

*Haider Mohammad Rasheed and Ameen Mosa Mohammad

ABSTRACT

Background: Cases of early onset ST segment elevation myocardial infarction (STEMI) is increasing worldwide including our region. In recent years the scientific community paid attention to non-classical risk factors like apolipoproteins. We aimed to assess the relation of apolipoprotein B (apoB) with early onset STEMI in Duhok, Kurdistan region of Iraq. Methods: This case-control study was performed at the Azadi Teaching Hospital and Azadi heart center in Duhok, Iraq, between May 2021 and December 2021. The study included 41 young patients (<50 Years) presented with acute STEMI and 48 healthy individuals with the matched age and sex and without a history of coronary artery disease (CAD) or ischemic stroke. Demographic, clinical and cardiovascular risk factors of the sample were studied. The apoB was measured and its relation to STEMI was assessed. Results: Cases had clustered of conventional risk factors and had significantly higher rates of these risk factors. Smoking was evidently more prevalent amid other risk factors. The apoB levels were higher among cases, but did not achieved a significant association with early onset STEMI (P>0.05). Conclusions: Despite of lacking direct association of apoB with early onset STEMI in this pilot study, the apoB has to be corelated with other CVS risk factors in the risk stratification for STEMI. Further cohort studies are warranted to assess the effect of apoB in the occurrence of STEMI with and without conventional CVS risk factors and to evaluate the sensitivity of this indicator in predicting ischemia.