WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Review Journal for Medical Science and Pharma Professionals
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ISSN 2457-0400

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Indexing

Abstract

A PRELIMINARY STUDY ON THE MOLLUSCICIDAL ACTIVITIES OF SOME SELECTED INDIGENOUS PLANTS AGAINST SCHISTOSOMOSIS INTERMIDIATE HOSTS (BULINUS AND BIOMPHALARIA SPP)

Gana David and Olanrewaju Comfort A.*

ABSTRACT

The molluscicidal activities of methanolic extracts of Acanthospermum hispidium, Ricinus cuminis and Vernonia amygdalina leaf and root against Biomphalaria pfeifferi and Bulinus globosus were investigated. Ten adults each of Biomphalaria pfeifferi and Bulinus globosus were exposed to different concentrations; 40, 80, 120, 160 and 200ppm of leaf and root extracts respectively. The snails were recovered after 24 hours of exposure. The lethal dose (LD50) of the three plants against Biomphalaria pfeifferi and Bulinus globosus were 34.24, 12.27 and 25.96ppm; and 43.66, 10.55 and 37.30ppm for leaf and root extracts respectively. The methanolic extracts of the three plants were very potent against B. globosus and B. pfeifferi at (x2=3.78, p<0.05), (x2= 3.03, p< 0.05), and (x2 = 3.37, p<0.05) for Acanthospermum hispidium, Ricinus cuminis and Vernonia amygdalina leaf extracts, and (x24.50, p<0.05), (x2= 2.52, p<0.05) and (x2 = 3.23, p<0.05) for root extracts. The results obtained showed that the leaf and root extracts of the three plants possess molluscicidal properties against the snails therefore they are suitable for biological application which offers a potentially simple, readily available, inexpensive and environmentally safe molluscicidal agents of plant origin for controlling urinary and intestinal schistosomosis and deserves further studies in order to identify and characterize its molluscicidal components; and to ascertain their effectiveness on the field.

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