WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

*Nagham Ismael Ibrahim, Ekhlas Ahmed Faraj and Entesar M. Ali Hameed

ABSTRACT

Background: Prenatal and antenatal TORCH infections are linked to poor fetal outcomes and infertility. TORCH infections tend to have long lasting effects on a person's life. Since Iraq's Mosul province lacks baseline serological data on the immunity to the TORCH infection during pregnancy, it is essential to enhance prenatal care and evaluate the immunological status of pregnant mothers in order to give suitable counseling and infection control measures. Objectives: Is to assess the seropreva lence of TORCH infection during pregnancy among ladies from Mosul city. Methods: This is cross-sectional study included 200 pregnant women recruited from the Gynecology and Obstetrics Department at Al Khansa’a Teaching Hospital and Al Sukar Primary health care center, from January 2024 to April 2025. The questionnaire includes five sections, section one for demographic information, section two for the patients’ presenting complaints, section three for the investigation results. Results: The study included 2 00 pregnant ladies who did TORCH test, the majority of them are presented to the study setting for checking during first trimester. TORCH positive seroprevalence was present among 129 (69.5%) patients of the study participants. Additionally; IgG antibody a gainst Toxoplasma was found to be the positive among (37.5%) followed by IgG antibody against Cytomegalovirus among (29.5%) then IgG against Rubella among (24%), while IgM against Toxoplasma was prevalent among (15.5%) and IgG against Herps simplex was pr evalent among (4.5%). The study found that patients with positive history of cat contact during antenatal life and patients with positive history of blood transfusion were statistically significant different for having positive TORCH seroprevalence (P valu e = 0.031). in contrast to housewives were less likely to have positive TORCH seroprevalence than employed ladies with statistically significant difference (P value <0.001). Positive seroprevalence of toxoplasmosis infections (IgM and IgG) was found to be significantly correlated with age group of less than 25 years (P value <0.001), while positive seroprevalence for Cytomegalovirus infection was founded to be significantly correlated with age group of more than 25 years (P value <0.001). Furthermore; less than 25 years old age group was found to have infection with mono agent (P value = 0.047). In contrast to those of more than 25 years old which were found to have two agent infection (P value <0.001). Lastly; patients with previous history of first trimest er abortion were found to have a significant two agent infection than ladies which were presented for checking or having offspring with congenital anomalies (P value <0.001). Conclusion: Mosul h as a relatively high rate of TORCH infection seroprevalence. Long term IgM persistence makes it difficult to discriminate between acute and chronic infections, therefore; other techniques such as molecular studies like PCR, are one way to distinguish betwe en active infections. Additionally, routine health education campaigns and TORCH vaccination will aid in lowering the incidence of these illnesses.