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World Journal of Advance Healthcare Research (WJAHR)Honored the authors with best paper award, monthly based on the innovation of research work. Best paper will be selected by our expert panel.
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IN SILICO STUDIES ON DENGUE AND HANTAAN VIRAL STRUCTURAL PROTEINS WITH SELECTED CORIANDER SATIVUM L CONSTITUENTS
Nagarjun N., Aniruddha B. S., Ashwini B. M., Mahesh K., Nagarathna Amresh and *Balasubramanian Sathyamurthy
Coriander sativum L belongs to family Umballiferae/Apiaceae. The constituents of Coriander sativum L are used as herbs in Ayurvedic medicine. They are believed to possess anti-diabetic, anti microbial, anti inflammatory properties. The GCMS results showed the presence of 7 compounds in Coriander sativum L with a wide variety of biological activities. The comparative study of Dengue and Hantaan viruses with their structural protein for dengue were carried out through In Silico methods. In this study we examined the binding affinities of 7 ligands with 4 proteins of both dengue and Hantaan viruses. By our virtual screening and molecular docking result, we found that the Compound Hexadecanoicacid, methyl ester had the highest binding affinity with these proteins.[Full Text Article]