WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

Eyyad Ali Aysha*, Fadi Kash and Ghanem Ahmad

ABSTRACT

Background: Lips provide some important roles from social interaction and expressing emotion to oral competence and swallowing, and there were wide range of reconstructive options. Aim: The purpose of this study was to evaluate final outcome of acquired lip defects reconstruction. Materials and Methods: A retrospective study was conducted for the period five years (May 2017 – May 2021) at Tishreen University Hospital in Lattakia-Syria. The study included a group of patients with acquired lip defects who underwent reconstruction with various methods. Patients were classified into three group according to the size of defect; group I included patients with size defect smaller than one-third of lip (14 cases), group II included patients with defects in the size one-third to two-third(17cases), and group III included patients with defects larger than two- third of lip (1 case). Results: A total of 38 patients, 25 males (65.8%) and 13 females (34.2%) with a mean age of 59.8±6.2 years were included in the study. Cancer was the most frequent etiology of defects in 30 cases (79%), followed by trauma in 8 cases (21%). Defects were located more frequently on lower lip in 34 cases (89.5%) and defects were full- thickness in 32 cases (84.2%). 53. 1% of the defects were in the size one-third to two- third of the lip, and methods of reconstruction varied according to the size of defect. Primary closure was performed in 100% of the patients in group I. In group II; primary closure was applied in 64.7%, Karapandzic flap in 23.5%, and Estlander flap in 11.8%. Karapandzic flap was applied in patient with defect size larger than two- third of the lip. The rate of complication in group I was 28.6 % and hypertrophic scars represented the most frequent complication which observed in 14.3%, whereas in group II complications developed in 52.9% and blunting of the commissure was occurred more frequently (23.5%). Flap necrosis represented the observed complication in group III. Complications developed significantly with advanced age and in presence of smoking(p

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