WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

Dr. Latifa Baiazid*, Prof. Dr. Hasan Saleh and Prof. Dr. Thawra Naiseh

ABSTRACT

Background: Infertility is one of the basics of gynecological treatments, and its problems affect many couples. objective: Our study aimed to evaluate the effect (three injections) of platelet-rich plasma (PRP) as a promising adjunctive therapy in thin endometriosis (TE). which did not achieve the required thickness of 7 mm, And the possibility of its role through multiple self-injection in improving implantation rates and pregnancy rates. Study design. The study was prospective trial which condcted in department of obstetrics and gynecology, Tishreen University Hospital, Lattakia, Syria approved by the ethics committee of Tishreen University, and all participants signed an informed written consent. Results The infusion was reinforced by being three infusions, that is, the second infusion was reinforced by the third infusion. PRPincreased the endometrial growth thickness in all cases. The biochemical pregnancy rate determined as positive beta-human chorionic gonadotropin (?-hCG) was 20%,; the ongoing pregnancy rate was 10%. So Multiple PRP application was therefore consistent with the probability of pregnancy, with an improvement in the rate. Conclusions The Intrauterine autologous platelet- rich plasma( PRP) infusion is a safe, easily accessible, effective, inexpensive. In our study, the results achieved a clear improvement in the thickness of the lining, and a slight improvement in pregnancy and childbirth outcomes,The small sample may be an important factor, but it itself showed an improvement in the results as a first attempt and study.

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