WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

Aishwarya S. Patil*, S. V. Pimpale and B. S. Wakure

ABSTRACT

Background: India is very traditional country and we are lucky to have treasure house of traditional medicine. now a days ayurvedic medicine has been a boon in the treatment of many disastrous disease. Rheumatoid arthiritis is one of the autoimmune disorder which is due to faulty metabolism of body and stess.it becomes chronic inflammatory disorder which result in severe pain.alopathic medicine can reduce pain but the root cause remain untreated. Main body-in this paper we study on combination of most potent herbal drugs like ashwagandha,safed musli,mahayogiraj guggul and maharasandi kwath that have clinically proven antiinfflamatory,analgesic and anti arthritic activities when used alone. now a days such kind of inflammatory disorders increases day by day due to change in lifestyle. inflammation in any part of the body result either due to physical injury or due to internal faulty metabolism of the body.faulty metabolism of the body may be due to improper diet irregular food timings,anger,stress. As per Ayurveda, faulty metabolism of body produces Aam (toxins or Reactive Oxygen Species). These Aam or Reactive Oxygen Speices (ROS) are highly unstable compounds and are key signaling molecules that play an important role in the progression of inflammatory disorders. As per Ayurveda ROS leads to imbalance in the three main pillars of the body that is vata-pitta-kapha. Under normal conditions, ROS levels are controlled by the body’s complex antioxidant defense system and there is an equilibrium between ROS formation and degradation. Overproduction of ROS and/or inadequate antioxidant defense disturbs this equilibrium in favor of ROS upsurge that results in oxidative stress. A deficiency in the body’s natural antioxidant defense mechanisms has been implicated as the etiological or pathological factor in several clinical disorders. Short conclusion- The accessible logical information support the end that ashwagandha,safed musli,mahayogiraj guggul,maharasnadi kwath are genuinely powerful regenerative tonic (Rasayana of Ayurveda), because of its different pharmacological activities like enemy of stress, neuroprotective, antitumor, ligament pain relieving, calming and so on.

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