WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Review Journal for Medical Science and Pharma Professionals

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

World Journal of Advance Healthcare Research (WJAHR) has indexed with various reputed international bodies like : Google Scholar , Index Copernicus , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , Cosmos Impact Factor , Scientific Indexing Services (SIS) , UDLedge Science Citation Index , International Impact Factor Services , International Society for Research Activity (ISRA) Journal Impact Factor (JIF) , IFSIJ Measure of Journal Quality , Scientific Journal Impact Factor (SJIF) , International Scientific Indexing, UAE (ISI) (Under Process) , International Impact Factor Services (IIFS) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Academia , Scope Database , 

ISSN 2457-0400

Impact Factor  :  6.711

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Indexing

  Indexing

  • Google Scholar
  • Index Copernicus
  • SOCOLAR, China
  • Research Bible, Fuchu, Tokyo. JAPAN
  • Cosmos Impact Factor
  • Scientific Indexing Services (SIS)
  • UDLedge Science Citation Index
  • International Impact Factor Services
  • International Society for Research Activity (ISRA) Journal Impact Factor (JIF)
  • IFSIJ Measure of Journal Quality
  • Scientific Journal Impact Factor (SJIF)
  • International Scientific Indexing, UAE (ISI) (Under Process)
  • International Impact Factor Services (IIFS)
  • Web of Science Group (Under Process)
  • Directory of Research Journals Indexing
  • Scholar Article Journal Index (SAJI)
  • International Scientific Indexing ( ISI )
  • Academia
  • Scope Database

Abstract

THE POTENTIAL IMPACT OF PHARMACOGENETICS ON PERSONALIZED MEDICINE AND MEDICATION COMPLIANCE: A REVIEW

M. D. M. Fernando*, N. H. K. S. Senathilake and B. G. D. N. K. De Silva

ABSTRACT

The expansion of gene cloning, DNA genotyping and sequencing have greatly influenced the enlargement of the applications of Pharmacogenetics in drug discovery and development. It is used to unveil inherited genetic alterations in different drug metabolic pathways leading to varied pathological and therapeutic response. Personalized medicine is a medical model that tailor therapy with the best response and maximum safety limits to secure better patient care. It is tailored to the different characteristics of individual patients that is relied on person's distinctive genetic and molecular profile making them vulnerable to different diseases. However, therapeutic response is largely dependent on medication compliance that generally describes the extent to which patients correctly take medications by strictly obeying to the medical advises. In addition, it is based on the factors such as getting prescriptions filled, remembering to take medication on time, correct use of home medical devises, self-directed exercises, self-care, therapy sessions, and comprehending the directions.

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