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Abstract
IMPACT OF BMI ON CLINICOPATHOLOGICAL PARAMETERS AMONG THE PATIENT WITH BREAST CANCER
Lobna Saleem Obaid and *Ass. Prof. Dr. Sura Salman Ejam
ABSTRACT
Background: Breast cancer is the second most common cancer in the world and by far the most frequent cancer among women with an estimated 1.67 million new cancer cases diagnosed in 2012 (25% of all cancers). Breast cancer allocated into Luminal, HER2 augmented and basal subtype according to immunohistochemically indicators like ER, PR and HER2/neu. High body mass index (BMI) associated with more aggressive tumor behavior and a poor prognosis. Objective: The goal of this study is to determine the impact of BMI on molecular subtypes defined by (ER), (PR), and (HER2/neu) expression, histopathological types, grade and stage of breast carcinoma in pre- and postmenopausal patients. Method: This study carried out on (70) cases of breast cancer. Results: no significant differences between BMI means according to immunohistochemistry of breast. Cancer in perimenopause and postmenopausal. No significant association between histopathological subtypes, .grade and stage of breast cancer and BMI among study sample. Conclusions: The obese.patients constitute the largest percentage of women with breast carcinoma. Occurrence of large. Percentage of invasive ductal .carcinoma of (NOS) among the obese women.
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