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BIOLOGICAL EVALUATION OF IN-VIVO ANALGESIC AND ANTI-INFLAMMATORY EFFECTS OF PAEDERIA FOETIDA ROOT EXTRACT
Kurra Sruthi* and Kodi Gnaneshwari
The ethanolic root extract of Paederia foetida was evaluated for its analgesic and anti-inflammatory activities using different models of Pain and Inflammation. The analgesic activity of Paederia foetida was carried out using tail-flick, eddy’s hot plate and acetic acid induced writhing response in mice. Further in-vivo anti-inflammatory study was performed using carrageenan- induced rat paw edema in rats. The ethanolic root extract of Paederia foetida at a dose level of 100 and 200 mg/kg were tested for its therapeutic potential. The results were found to be encouraging in all animal models and the results were tabulated in detailed. Paederia foetida root extract possess significant analgesic and anti-inflammatory activities against various models of inflammation and pain.[Full Text Article]